NIHR/Wellcome Trust
Cambridge Clinical Research Facility

About Us Top

We specialise in supporting researchers, especially those with experimental medicine projects and early phase clinical trials, in adults and children. We are funded by the National Institute for Health Research (NIHR) to provide dedicated facilities to support experimental medicine clinical research. We are one of 19 NIHR Clinical Research Facilities.

We have three units: the NIHR/Wellcome Trust Clinical Research Facility (CRF), an NIHR Clinical Investigation Ward (CIW), and a CRF Satellite unit. Together, these comprise the Addenbrooke's Clinical Research Centre (ACRC) – a safe, well-equipped and professionally staffed research facility.

The facility employs highly trained staff skilled in chemotherapy and monoclonal antibody drug administration, endoscopy procedures and metabolic and physiological measurement. Within the Metabolic Research Area (MRA) we have equipment for DXA, BOD POD, direct/indirect calorimetry and whole body composition measurement.

Facilities For Research Top

Facilities include eleven 24/7 inpatient beds (in the CRF) and seven day-case beds (in the CIW) for interventional treatments. Outpatient and Investigation rooms are available Monday to Friday from 8am – 8pm. We also have a dedicated Play Room to support studies in children.

Facilities are also available for audiology, dietetic interventions, diet manipulations, sample handling and processing, with both university and NHS IT systems, including wifi access.

From first contact, our highly experienced staff can not only support your research but can guide you through any necessary administrative processes - from governance and indemnity issues to best clinical practice and staff education.

We currently support over 220 research studies, with the majority of these studies involving either medium or high-intensity interventions, in both adults and children.

Apply To Use Our Facilities Top

All research undertaken within the ACRC is reviewed by the Scientific Advisory Board (SAB). The membership of the SAB is broad-based to optimise the assessment of any application from a range of diverse disciplines.

Our Director is Professor Krishna Chatterjee and our Head of Clinical operations is Caroline Saunders.

Studies are first assessed in detail for scientific merit by a nominated SAB member, before the board as a whole considers and approves the appropriate allocation of resources for any project. The SAB meets on a monthly basis.

Application submission dates - 2014 SAB meetings - 2014/15
16 January 2014 6 February 2014
13 February 2014 6 March 2014
13 March 2014 3 April 2014
10 April 2014 1 May 2014
15 May 2014 5 June 2014
12 June 2014 10 July 2014
17 July 2014 7 August 2014
14 August 2014 4 September 2014
11 September 2014 2 October 2014
16 October 2014 6 November 2014
13 November 2014 4 December 2014
18 December 2014 8 January 2015

If you require an application pack or need further information please click or contact;

Click here to download the ACRC Application Form

Click here to download the ACRC User Guidelines (2013)

Click here to download the ACRC Operational Policy

Click here to send an email for further information


Caroline Saunders
(Head of Clinical Operations)
Ext. 01223 596057
Int. x6057
caroline.saunders@addenbrookes.nhs.uk

To View Availability For Booking Patients/Participants Top

Please click to view the CRF facility calendar.

Please click to view the CIW facility calendar.

Education Top

Our Education team provides service-specific training and Education for all Addenbrooke's Clinical Research Centre (ACRC) staff and others using the facility. Induction, emergency scenario training, study-specific training, research skills training and clinical skills training – delivered locally and regionally. All nurses joining the unit are provided with induction training.

Kornelia Hathaway is our Education and Training Manager. kornelia.hathaway@addenbrookes.nhs.uk

Courses providing an introduction for professionals new to working in Clinical Research;

Nationally recognised training and education documents co-authored by ACRC staff;

Patient and Public Involvement (PPI) Top
... research for you, with you

We believe that excellence in research is best achieved by involving and engaging patients and the public in our work, to inform the way we deliver and develop our services, to understand and improve patient experience, to share and learn from our experiences and to work collaborative across organizations where joint activities can add most value. Our priorities are about putting people first in research and supporting activities that enhance meaningful patient and public involvement, engagement and participation.

Involvement

Our Children's Non-Executive Board was established in 2013 to enable children to have a voice in our service development, to input into the design of generic and study specific patient information and to try out metabolic measurement kit. Membership includes children who have participated in studies on the CRF, children who have never participated in research, parents and members of staff.

Activities and outputs:

  • Children's Survey
  • Children's Non-Executive Board
  • Age specific Photo Stories
  • Children's Activity Menu
  • Publications
  • Public events

Engagement

We regularly hold and take part in local and national open days, public meetings, presentations to: patient groups, local schools, visiting students. We also contribute to local media publications; Matters Magazine - Autumn 2013.
Research related 'good news' stories and 'case studies' are displayed around the unit to share our work with patients and the public.

Forthcoming events (links to):

Participation

Many of our patients are recruited into research studies via specific volunteer groups these include:
The Clinical Research Facility healthy volunteer metabolic reference measurement study:
crf-volunteer@medschl.cam.ac.uk

The Cambridge BioResource healthy volunteer and patient panels:
http://www.cambridgebioresource.org.uk

Cambridge NIHR Biomedical Research Centre Patient Panel:
Joann.leeding@addenbrookes.nhs.uk

NIHR BioResource: Rare Disease patient and healthy volunteer panels:
NIHR BioResource - How to Join

We also provide meeting room facilities for investigators to hold study specific patient focus group meetings.

Collaboration and sharing best practice

Our PPI leads have established links with local and national groups working collaboratively on many activities, events and initiatives including workshops, conferences, patient groups, staff groups from across the NIHR.

Key local PPI contacts:

NIHR/Wellcome Trust Cambridge Clinical Research Facility
pippa.bayfield@addenbrookes.nhs.uk

West Anglia Comprehensive Local Research Network
justine.hill@addenbrookes.nhs.uk

Cambridge NIHR Biomedical Research Centre
joann.leeding@addenbrookes.nhs.uk

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